Anand_Padmanabhan.jpg

Anand Padmanabhan, MD, PhD

Medical Director, Therapeutic Services
BloodCenter of Wisconsin

Associate Investigator
Blood Research Institute

Assistant Professor of Pathology
Medical College of Wisconsin

Contact Information
Phone: (414) 937-6045
Fax: (414) 933-6803
E-mail: Anand.Padmanabhan@bcw.edu

Transfusion Medicine
Dr. Padmanabhan is a member of the Medical Sciences Institute of the BloodCenter of Wisconsin working in collaboration with Richard H Aster, M.D. His area of research focus is Heparin induced Thrombocytopenia and Thrombosis (HIT), a major cause of morbidity and mortality in patients: 1-5% of patients on heparin therapy go on to develop this condition. The focus of his studies is on defining the immunological mechanism by which HIT antibodies cause thrombocytopenia and thrombosis and are aimed at improving diagnosis and treatment of this serious complication of heparin therapy.

Grants
CURRENT
 
2012-2014
Role of IgA and IgM Immunoglobulins in Heparin-induced Thrombocytopenia and Thrombosis (HIT)
Role: Principal Investigator
Funding Source: National Blood Foundation

2012-2013
A Controlled Evaluation of the Spectra Optia Apheresis System's Granulocyte/Polymorpho-nuclear (PMN) Cell Collection Procedure
Role: Principal Investigator
Funding Source: Terumo BCT
 
 
COMPLETED

2012-2013
Role of IgA and IgM Immunoglobulins in Heparin-induced Thrombocytopenia and Thrombosis (HIT)
Role: Principal Investigator
Funding Source: CTSI of Southeastern Wisconsin

2010-2011
Evaluation of the Spectra Optia Apheresis System Mononuclear Cell (MNC) Collection Procedure in Healthy Blood Donors.
Role: Principal Investigator
Funding Source: Caridian BCT
 
2010-2011
Evaluation of Amicus Therapeutic Plasma Exchange (TPE) Procedure
Role: Co-PI (PI: J. Gottschall).
Funding Source: Fenwal, Inc

Curtis Jones
Assistant Research Technologist

Therapeutic Apheresis

 

Publications
Peer Reviewed 
  • Arinsburg SA, Skerrett DL, Karp JK, Ness PM, Jhang J, Padmanabhan A, Gibble J, Schwartz J, King KE, Cushing MM. Exclusion of female plasma donors significantly reduces transfusion-related acute lung injury, Transfusion, 2011, Nov 7
  • Stotler B*, Padmanabhan A*, Devine P, Wright J, Spitalnik SL, Schwartz J. Requirements in Obstetric Patients with Placenta Accreta, Transfusion, 2011 Dec. * both authors contributed equally
  • Serban G, Whittaker V, Fan J, Liu A, Manga K, Khan, M, Kontogianni K, Padmanabhan A, Cohen D, Suciu-Foca N, Raner L, Colovai, AI. Significance of immune cell function monitoring in renal transplantation after thymoglobulin induction therapy.Human Immunology 2009 Nov; 70(11):882-90
  • Padmanabhan A, Slotky R, Jhang JS, Dael S, Crowder T, Colovai AI and Schwartz J. 2009. Use of the Hematopoietic Progenitor Cell Parameter in Optimizing Timing of Peripheral Blood Stem Cell Collection. Vox Sang. 2009 Aug;97(2):153-9.
  • Padmanabhan A, Ratner LE, Jhang JS, Duong JK, Markowitz GS, Vasilescu ER, Crew RJ and Schwartz J. 2009. Comparative Outcome analysis of ABO-incompatible and Positive Crossmatch Renal Transplantation: A Single Center Experience. Transplantation. 2009 Jun 27;87(12):1889-96
  • Anand P and Gruppuso PA. 2006. Rapamycin inhibits liver growth during refeeding in rats via control of ribosomal protein translation but not cap-dependent translation initiation. J Nutrition. 2006 Jan;136(1):27-33.
  • Anand P and Gruppuso PA. 2005. The regulation of hepatic protein synthesis during fasting in the rat. J Biol Chem. 280(16):16427-36.
  • Gruppuso PA, Boylan JM, Anand P and Bienieki TC. 2005 Effects of maternal starvation on hepatocyte proliferation in the late gestation fetal rat. Pediatr Res. 57(2):185-91.
  • Anand P, Boylan JM, Ou Y and Gruppuso PA. 2002. Insulin signaling during perinatal liver development in the rat. Am J Physiol Endocrinol Metab. 283(4):E844-52.
  • Boylan JM, Anand P and Gruppuso PA. 2001. Ribosomal protein S6 phosphorylation and function during late gestation liver development in the rat. J Biol Chem. 276(48):44457-63.

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